Thermo Fisher Scientific TYRO3 Monoclonal Antibody (10E11)

Applications and Tested Dilution

Product Specifications

Product Specific Information

MA5-15505 targets TYRO3 in indirect ELISA and Western blot applications, showing reactivity with human samples.
The immunogen is a purified recombinant extracellular fragment of human TYRO3 fused with an hIgGFc tag expressed in HEK293 cells.
MA5-15505 detects TYRO3, which has a predicted molecular weight of approximately 96.9 kDa.

Target Information

TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces extracellular signals into the cytoplasm by binding to ligands such as TULP1 or GAS6.
It regulates physiological processes including cell survival, migration, and differentiation.
Ligand binding induces dimerization and autophosphorylation of TYRO3, providing docking sites for downstream signaling molecules.
Following activation, TYRO3 plays roles in neuron protection from excitotoxic injury, platelet aggregation, signal transduction, cell adhesion, and cytoskeleton reorganization.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.