Thermo Fisher Scientific MAPK7 Monoclonal Antibody (OTI3H2), TrueMAB

Thermo Fisher Scientific MAPK7 Monoclonal Antibody (OTI3H2), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

MAPK7 (ERK5) is a serine/threonine kinase belonging to the MAP kinase family, involved in cellular processes such as proliferation, differentiation, transcription regulation, and development.
Activated by MAP2K5/MEK5, MAPK7 translocates to the nucleus in response to extracellular signals to regulate gene expression through phosphorylation of transcription factors.
Gene deletion in mice leads to defective cardiovascular development and embryonic lethality.
ERK5 is expressed in adult tissues including heart, placenta, lung, kidney, and skeletal muscle, but not in liver.
Four alternatively spliced transcript variants encoding two distinct isoforms have been reported.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(해당 제품 관련 이미지가 있을 경우 여기에 배치)