Thermo Fisher Scientific VSIG2 Monoclonal Antibody (OTI1H2), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

CTXL, also known as VSIG2, is a member of the immunoglobulin (Ig) superfamily with characteristics of both antigen-specific receptors and adhesion molecules.
This single-pass, type I membrane protein contains a signal peptide, an extracellular V-type Ig-like domain, a C2-type Ig-like domain, and a cytoplasmic tail.
Expression is high in the stomach, colon, prostate, trachea, and thyroid gland, with lower levels in bladder and lung tissues.
CTXL is not expressed in the thymus and is developmentally regulated, potentially involved in thymocyte selection.
It localizes to junctional complexes between endothelial and epithelial cells and may contribute to cell-cell adhesion and leukocyte transmigration.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.