Thermo Fisher Scientific Avian Influenza NS1 Synthetic Peptide
조류 인플루엔자 NS1 단백질의 C-말단 14개 아미노산 서열에 대응하는 합성 펩타이드. 비결합 상태의 정제된 액상 시약으로 연구용에 적합. PBS(pH 7.2)와 0.1% BSA, 0.02% sodium azide 포함. -20°C에서 보관.
- 카탈로그번호
- PEP0395
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Avian Influenza NS1 Synthetic Peptide
Thermo Fisher Scientific Avian Influenza NS1 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the carboxy terminus of avian influenza NS1.
Target Information
Influenza A H1N1 NS (Non-structural protein 1, NS1A, or NS1) is a 234-amino-acid protein belonging to the Influenza A virus (strain A/Swine/Iowa/15/1930 H1N1), which infects aves, humans, and pigs.
NS1 forms a homodimer located in the nucleus of uninfected or transfected cells, and in the cytoplasm of infected cells.
It binds and inhibits cellular proteins CPSF4 and PABPN1, required for 3’-end processing of pre-mRNAs, leading to accumulation of unprocessed pre-mRNAs and suppression of host protein synthesis.
This mechanism allows the virus to evade interferon synthesis and prevents the establishment of an antiviral state.
NS1 also inhibits EIF2AK2/PKR activation early in infection, helping the virus evade host defense.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.