Thermo Fisher Scientific Human PAK2 Synthetic Peptide
Human PAK2 단백질의 N-말단 14개 아미노산 서열을 기반으로 한 합성 펩타이드. 항체 PA5-20254와 함께 차단 펩타이드로 사용 가능. 세포골격 조절, 세포 이동, 세포주기 및 생존 관련 연구에 적합. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the amino terminus of human PAK2.
PEP-0390 can be used as a blocking peptide with polyclonal antibody PA5-20254.
Target Information
PAK2 (serine/threonine-protein kinase PAK2) is a serine/threonine kinase that plays a role in various signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis, and proliferation.
It acts as a downstream effector of the small GTPases CDC42 and RAC1. Activation by binding of active CDC42 and RAC1 results in a conformational change and subsequent autophosphorylation on several serine and/or threonine residues.
Full-length PAK2 stimulates cell survival and cell growth. PAK proteins are critical effectors linking Rho GTPases to cytoskeleton reorganization and nuclear signaling.
PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for small GTP-binding proteins Cdc42 and RAC and are implicated in a wide range of biological activities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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