Thermo Fisher Scientific DAXX Polyclonal Antibody
DAXX 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 Immunoprecipitation에 적합하며, 액상 형태로 4°C에서 보관. 인간 DAXX 단백질 466–516 영역을 면역원으로 사용. 연구용으로만 사용 가능.
- 카탈로그번호
- A301353Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific DAXX Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 466 and 516 of human death-associated protein 6 (DAXX) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and cytoplasm. It interacts with various proteins such as apoptosis antigen Fas, centromere protein C, and transcription factor E26 oncogene homolog 1.
In the nucleus, it functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by sequestration into promyelocytic leukemia nuclear bodies or nucleoli.
This protein associates with centromeres during G2 phase and may regulate apoptosis in the cytoplasm. Subcellular localization and function are modulated by post-translational modifications including sumoylation, phosphorylation, and polyubiquitination.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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