Thermo Fisher Scientific CD19 Monoclonal Antibody (1G3)
CD19 단백질을 인식하는 Mouse IgG2a 형 단클론 항체로, 인간 시료에 반응합니다. Western blot과 ELISA에 사용 가능하며, 비결합형 액상 형태로 제공됩니다. B세포 표면 CD19 연구 및 백혈병 관련 연구에 적합합니다.
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Thermo Fisher Scientific CD19 Monoclonal Antibody (1G3)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G3 |
| Immunogen | CD19 (NP_001761, 98–187 a.a) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
QPGPPSEKAW QPGWTVNVEG SGELFRWNVS DLGGLGCGLK NRSSEGPSSP SGKLMSPKLY VWAKDRPEIW EGEPPCVPPR DSLNQSLSQD
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on 100% of peripheral B cells and may also be found on myeloid leukemia cells, particularly of monocytic lineage. CD19 serves as a signal-amplifying coreceptor for the B cell receptor (BCR) and plays a central regulatory role in B cell proliferation and differentiation. Mutations in CD19 can lead to hypogammaglobulinemia, while overexpression is associated with B cell hyperactivity.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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