Thermo Fisher Scientific CD19 Monoclonal Antibody (1G3)
CD19 단백질을 표적으로 하는 Thermo Fisher Scientific의 Mouse IgG2a 단일클론 항체(1G3)로, 인간 시료에 반응합니다. Western blot, ELISA, Immunoprecipitation에 사용 가능하며, 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
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- H00000930-M01
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
| Immunoprecipitation (IP) | 1–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G3 |
| Immunogen | CD19 (NP_001761, 98–187 a.a.) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
QPGPPSEKAW QPGWTVNVEG SGELFRWNVS DLGGLGCGLK NRSSEGPSSP SGKLMSPKLY VWAKDRPEIW EGEPPCVPPR DSLNQSLSQD
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on 100% of peripheral B cells (kappa or lambda light chains) and can also be found on myeloid leukemia cells, especially monocytic lineage.
CD19 functions as a signal-amplifying coreceptor for the B cell receptor (BCR), regulating B cell activation and proliferation. Mutations lead to hypogammaglobulinemia, while overexpression causes B cell hyperactivity.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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