Thermo Fisher Scientific ACVR2B Recombinant Rabbit Monoclonal Antibody (307)

Applications

ELISA

• Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire

This antibody has specificity for Mouse ACVR2B/ACTRIIB.

Target Information

ACVR2B is a type II member of the TGF-beta family of receptor serine/threonine kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily, sharing amino acid homology with conservation of 7 of the 9 cysteine residues common to all TGF-beta forms.

To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, IIA, IB, and IIB. Additionally, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.