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Thermo Fisher Scientific Phospho-c-Jun (Ser243) Polyclonal Antibody
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Phospho-c-Jun (Ser243) 폴리클로날 항체로 인간, 마우스, 랫트에 반응. Western blot, IHC, ICC, IP 등 다양한 응용 가능. c-Jun의 Ser243 인산화 형태를 특이적으로 검출. 순차 크로마토그래피로 정제된 고순도 액상 항체.
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- pk
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마지막 업데이트 2025. 08. 03. 오전 11:51
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Thermo Fisher Scientific PA5104747 Phospho-c-Jun (Ser243) Polyclonal Antibody 100 ul pk판매 단위 pk ·
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627,600원VAT 포함 690,360원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-c-Jun (Ser243) Polyclonal Antibody
Thermo Fisher Scientific Phospho-c-Jun (Ser243) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human JUN (Accession P05412), corresponding to amino acid residues around phosphorylated Ser243 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816220 |
Product Specific Information
This antibody detects endogenous levels of c-Jun only when phosphorylated at Serine 243.
Target Information
c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3, leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. It is involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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