Thermo Fisher Scientific Phospho-c-Jun (Ser243) Polyclonal Antibody
Phospho-c-Jun (Ser243) 특이적 폴리클로날 항체로 Western blot에 적합. Human, Mouse, Rat 등 다양한 종에 반응. 항원 친화 크로마토그래피로 정제된 고순도 항체. -20°C 보관, 연구용 전용.
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Applications
Western Blot (WB)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues around pSer243 of human c-Jun |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 145 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10983652 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes NR5A1 activity when phosphorylated by HIPK3, leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. It is also involved in KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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