Thermo Fisher Scientific UBA52 Polyclonal Antibody
UBA52 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. IHC(P)에서 1:50–1:100 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(glycerol 포함) 용액 형태로 제공. 인간 단백질에 반응하며 내인성 유비퀴틴 단백질 검출에 적합.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human Ubiquitin (UBA52, UniProt ID: P62987-1, antigen range 53–75) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635208 |
Product Specific Information
This antibody detects endogenous levels of total ubiquitin protein.
Target Information
Ubiquitin is a highly conserved protein essential for targeting cellular proteins for degradation by the 26S proteasome. It is synthesized as a precursor either as polyubiquitin chains or as a single ubiquitin fused to another protein.
The UBA52 gene encodes a fusion protein of ubiquitin (N-terminus) and ribosomal protein S27a (C-terminus). Upon expression, the protein is post-translationally processed to generate free ubiquitin monomer and ribosomal protein S27a.
Ribosomal protein S27a, a component of the 40S ribosomal subunit, belongs to the S27AE family, contains C4-type zinc finger domains, and is located in the cytoplasm.
Pseudogenes derived from this gene exist in the genome. Similar fusion proteins include ribosomal protein L40 (with ubiquitin) and ribosomal protein S30 (with ubiquitin-like protein fubi).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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