Thermo Fisher Scientific SPTY2D1 Polyclonal Antibody
Human SPTY2D1 단백질을 인식하는 Rabbit Polyclonal 항체로, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 완충액에 보관됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA565486
- 판매단위
- pk
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human SPTY2D1. Recombinant protein control fragment (Product #RP-104840) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663640 |
Product Specific Information
Immunogen sequence:
SGPGRSISGSI PAGRTVSNSV PGRPVSSLGP GQTVSSSGPT IKPKCTVVSE TISSKNIISR SSNGQMNGMK PPLSGYRAAQ GPQRLPFPTG YKRQREYEE
- Highest antigen sequence identity to the following orthologs:
- Mouse: 86%
- Rat: 83%
Target Information
Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin (PubMed:26109053).
Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription (PubMed:26109053).
Binds DNA and histones and promotes nucleosome assembly (in vitro) (PubMed:23378026, PubMed:26109053).
Facilitates formation of tetrameric histone complexes containing histone H3 and H4 (PubMed:26109053).
Modulates RNA polymerase 1-mediated transcription.
Binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holliday junction DNA (PubMed:23378026).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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