Thermo Fisher Scientific CD1b Polyclonal Antibody
Human CD1b 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot 및 IHC(Paraffin) 검증 완료. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 용액 형태로 제공. 연구용으로 세포 내 CD1b 발현 분석에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CD1B (Product #RP-90350) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2789931 |
Product Specific Information
Immunogen sequence:
IHGWDSDSGT AIFLKPWSKG NFSDKEVAEL EEIFRVYIFG FAREVQDFAG DFQMKYPFEI QGIAGCELHS GGAIVSFLRG ALGGLDFLSV KNASCVPSPE GGSRAQKFCA LIIQYQGIME TVRILLYETC PRYLLGVLNA GKAD
Target Information
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin.
CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells.
The human genome contains five CD1 family genes organized in a cluster on chromosome 1.
CD1 family members differ in their cellular localization and specificity for particular lipid ligands.
The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail and requires vesicular acidification to bind lipid antigens.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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