Thermo Fisher Scientific Carboxypeptidase A1 Polyclonal Antibody
사람 CPA1 단백질을 인식하는 토끼 폴리클로날 항체. 파라핀 포매 조직 면역조직화학(IHC-P)에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보존. 단백질 소화 관련 연구에 활용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CPA1 (Product # RP-92631) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping conditions | Wet ice |
| RRID | AB_2789932 |
Product Specific Information
Immunogen sequence:
MIEDVQSLLD EEQEQMFAFR SRARSTDTFN YATYHTLEEI YDFLDLLVAE NPHLVSKIQI GNTYEGRPIY VLKF
Target Information
CPA1 (Carboxypeptidase A1), also known as CPA, is a 419-amino-acid secreted monomeric protein highly expressed in pancreatic tissue. It functions as a pancreatic exopeptidase using zinc as a cofactor to catalyze the release of C-terminal amino acids from various proteins, playing a key role in protein digestion and degradation. CPA1 may also be involved in zymogen inhibition, helping to block enzyme activation pathways. Abnormal CPA1 levels are associated with pancreatic cancer, suggesting roles in tumor progression or suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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