Thermo Fisher Scientific ERAB Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000
• Publications: References

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:1,000
• Publications: References

Product Specifications

Product Specific Information

• Keep as concentrated solution.
• Predicted reactivity: Mouse (93%), Rat (91%), Xenopus laevis (83%), Rhesus Monkey (98%), Bovine (94%).
• Positive Control: 293T, HeLa, HepG2, Molt-4, Raji.
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily.
The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids.
The protein has been implicated in the development of Alzheimer’s disease, and mutations in the gene cause 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD).
Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.