Thermo Fisher Scientific Filensin Polyclonal Antibody
Filensin 단백질을 인식하는 토끼 폴리클로날 항체로, 인간 시료에 반응합니다. IHC(P) 및 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:5,000–1:10,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Filensin. Recombinant protein control fragment (Product # RP-99408). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641640 |
Product Specific Information
Immunogen sequence:
SAHECHDDEI QLYNEQIETL RKEIEETERV LEKSSYDCRQ LAVAQQTLKN ELDRYHRIIE IEGNRLTSAF IETPIPLFTQ SHGVSLSTGS GGKD
Highest antigen sequence identity to the following orthologs:
- Mouse: 79%
- Rat: 82%
Target Information
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element referred to as the beaded filament (BF). Mutations in this gene cause autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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