Thermo Fisher Scientific NGFR Recombinant Rabbit Monoclonal Antibody (117)
마우스 NGFR/P75 단백질을 인식하는 재조합 토끼 단클론 항체. Western blot과 ELISA에 적합하며 높은 특이성과 민감도를 제공. 보존제 무첨가 포뮬레이션으로 실험 재현성이 우수. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:25,000–1:50,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 117 |
| Immunogen | Recombinant Mouse NGFR/P75 Protein (Met1–Asn243) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785559 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
This antibody has specificity for Mouse NGFR/P75.
Target Information
Neurotrophic factors control the survival, differentiation, and maintenance of neurons in the peripheral and central nervous systems, as well as other neural crest-derived cell types. Developing sympathetic neurons are dependent upon nerve growth factor (NGF) during target competition in vivo.
Antibodies reacting specifically with NGFR p75 are valuable tools for detecting and characterizing NGFR p75, enhancing understanding of neuronal development, plasticity, and repair mechanisms.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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