Thermo Fisher Scientific SMC1 Polyclonal Antibody
Human SMC1A 단백질을 타겟으로 하는 Rabbit Polyclonal Antibody로, Western Blot에 적합. Protein A 및 Antigen affinity chromatography로 정제됨. PBS buffer에 0.09% sodium azide 포함. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 307–336 amino acids from the N-terminal region of human SMC1A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2900838 |
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins are essential for nuclear events requiring structural changes of chromosomes, such as mitotic chromosome organization, DNA recombination and repair, and global transcriptional repression. These proteins are conserved in eukaryotes and are crucial for mitotic chromosome dynamics.
SMC1 and SMC3 form a heterodimeric complex required for metaphase progression and sister chromatid cohesion. Mutations in the SMC1A gene can lead to Cornelia de Lange syndrome 2.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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