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Thermo Fisher Scientific CD16 Polyclonal Antibody
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Rabbit polyclonal antibody against human CD16 (FCGR3A). Validated for Western blot. Recognizes Fc region receptor involved in immune complex clearance and NK cell cytotoxicity. Supplied as liquid, 0.5 mg/mL in PBS with sodium azide. For research use only.
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마지막 업데이트 2025. 08. 05. 오후 04:33
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Thermo Fisher Scientific PA5116202 CD16 Polyclonal Antibody 400 ul pk판매 단위 pk ·
재고 확인 필요
656,000원VAT 포함 721,600원
Thermo Fisher Scientific · Thermo Fisher Scientific CD16 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 226–254 of the C-terminal region of human FCGR3A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2900836 |
Target Information
CD16 encodes a receptor that recognizes the Fc portion of immunoglobulin G and is involved in immune complex clearance, cellular cytotoxicity, and enhancement of viral infections. The gene FCGR3A shares high similarity with FCGR3B, located nearby on chromosome 1.
- Expression: FCGR3A is expressed on NK cells as a membrane glycoprotein; FCGR3B is expressed on neutrophils with a PI linkage.
- Clinical relevance: Mutations in FCGR3A are linked to immunodeficiency 20, recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia.
- Variants: Alternative splicing results in different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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