Thermo Fisher Scientific TRHR Polyclonal Antibody
TRH 수용체를 인식하는 Rabbit Polyclonal 항체로 다양한 종(인간, 개, 말, 설치류 등)에 반응. IHC(P)에서 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 19 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Horse, Human, Non-human primate, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human TRH Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551629 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Rat, Dog, Elephant, Horse (100%).
Target Information
TRH-R is a 398 amino acid integral membrane protein with six transmembrane domains and belongs to the G-protein coupled receptor 1 family. It acts as a receptor for the signaling hormone TRH and activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon binding with TRH. Reports suggest that TRH-R is a neurotransmitter and neuro regulator that controls dimerization of the TRH receptor and potentiates hormone-induced receptor trafficking. It is known to be widely expressed in the thyrotroph cells of the anterior pituitary.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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