Thermo Fisher Scientific AMACR Monoclonal Antibody (UMAB214), UltraMAB
AMACR 단백질을 인식하는 UMAB214 단클론 항체로, 인간 시료에 반응합니다. IHC, ChIP, Peptide Array 등에 사용 가능하며, 동결건조 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:2400 |
| ChIP assay (ChIP) | Assay-Dependent |
| Peptide Array (Array) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB214 |
| Immunogen | Full length human recombinant protein of human AMACR produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
P504S/AMACR (α-Methylacyl-CoA Racemase) is an essential enzyme in the β-oxidation of branched-chain fatty acids.
High expression of P504S protein is observed in prostatic adenocarcinoma but not in benign prostate tissue by IHC of paraffin-embedded samples.
Expression is also detected in premalignant prostate lesions such as high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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