Thermo Fisher Scientific SLC10A7 Polyclonal Antibody

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 0.25–2 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence: KSWMVSRQKKL LQTRGPLANL NNPEGLEYLS IKFGH
• Highest antigen sequence identity to orthologs: mouse 33%, rat 33%

Target Information

SLC10A7 (solute carrier family 10, member 7), also known as P7, is a 358 amino acid multi-pass membrane protein belonging to the sodium:bile acid symporter family.
It exists as seven alternatively spliced isoforms and is expressed at high levels in liver and lung, moderate levels in placenta, kidney, spleen, and thymus, and low levels in heart, prostate, and testis.

Members of the sodium:bile acid symporter family, such as NTCP (SLC10A1) and Asbt (SLC10A2), mediate active bile transport across liver and intestinal membranes.
Other family members, including SLC10A6, are involved in prohormone delivery in testis, placenta, adrenal gland, and other peripheral tissues.
Orphan carriers such as SLC10A7 remain uncharacterized, and their functions are currently unknown.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.