
Thermo Fisher Scientific GIPR (extracellular) Polyclonal Antibody
GIPR 단백질의 세포외 영역을 인식하는 Rabbit Polyclonal 항체. Western blot, IHC(F), Flow Cytometry에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS/BSA 완충액에 보관. 당뇨병 연구 등 GIP 수용체 관련 연구용으로 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:400 |
| Flow Cytometry (Flow) | 2.5 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)EGQTTGELYQRWER, corresponding to amino acid residues 25–38 of rat GIPR, Extracellular, N-terminus |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 25 µL, 50 µL, or 0.2 mL of double distilled water (DDW) depending on the sample size.
The antibody is shipped as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C for up to 1 week. For long-term storage, aliquot and keep at -20°C.
Avoid repeated freeze-thaw cycles. Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
GIPR encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, later shown to stimulate insulin release in the presence of elevated glucose.
Mice lacking this gene show higher blood glucose levels and impaired initial insulin response after oral glucose load.
Defects in this gene may contribute to the pathogenesis of diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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