Thermo Fisher Scientific DAZ3 Polyclonal Antibody
Human DAZ3 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합. KLH 결합 합성 펩타이드(445–474 aa) 면역원 사용. Protein A 및 항원 친화 크로마토그래피로 정제. 액상 형태, 4°C 또는 -20°C 보관.
- 카탈로그번호
- PA5116174
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 445–474 amino acids from the C-terminal region of human DAZ3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2900808 |
Target Information
This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and sequence variations exist. Each copy also contains a 10.8 kb region that may be amplified; this region includes five exons encoding an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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