Thermo Fisher Scientific ACVR1 Polyclonal Antibody
ACVR1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC에 사용 가능. Human 및 Rat 시료에 반응하며, KLH-conjugated synthetic peptide로부터 제작. 고순도 정제 및 안정적 보관이 가능한 액상 항체.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | View publication |
Product Specifications
| Category | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between amino acids 6–34 from the N-terminal region of human Activin Receptor Type IA (ACVR1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Ammonium sulfate precipitation, Size-exclusion, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2289122 |
Product Specific Information
This antibody is predicted to react with bovine based on sequence homology.
Target Information
Activin A receptor, type I (ACVR1) belongs to the transforming growth factor-beta (TGF-beta) superfamily of signaling proteins. ACVR1 mediates transcriptional responses in concert with activin type II receptors. Mutations in ACVR1 are associated with Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by heterotopic ossification, and with Epicanthus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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