Thermo Fisher Scientific ACVR2A Polyclonal Antibody
ACVR2A 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC에 사용 가능. 인간과 마우스에 반응하며, Activin/Myostatin 신호전달 연구에 적합. 고순도 정제 및 안정적 PBS buffer 제공.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ACVR2A Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: Not specified
- Publications: 1 publication available
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between amino acids 2–29 from the N-terminal region of human ACVR2A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Ammonium sulfate precipitation, Size-exclusion, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2289142 |
Product Specific Information
This antibody is predicted to react with bovine, chicken, mouse, and rat based on sequence homology.
Target Information
Activin A receptor kinase (ACVR2A) is a type II member of the TGF-beta family of receptor Serine/Threonine kinases.
ACVR2A is involved in the activin and myostatin signaling pathway.
Aliases: ACVR2, ACTRII
These receptors are transmembrane proteins composed of:
- Ligand-binding extracellular domain with cysteine-rich region
- Transmembrane domain
- Cytoplasmic domain with serine/threonine kinase activity
Type I receptors are essential for signaling, while type II receptors are required for ligand binding and expression of type I receptors.
Upon ligand binding, type I and II receptors form a stable complex, resulting in phosphorylation of type I receptors by type II receptors.
Type II receptors are constitutively active kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.