Thermo Fisher Scientific Cytohesin 3 Polyclonal Antibody
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Cytohesin 3 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. Protein A로 정제된 1 mg/mL 액상 제품이며 -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Cytohesin 3, amino acids 301–400 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
GRP1 (general receptor for phosphoinositides-1) contains a Pleckstrin homology (PH) domain and a Sec7 domain.
- The PH domain binds phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3).
- The Sec7 domain catalyzes guanine nucleotide exchange of ADP-ribosylation factor (ARF) proteins.
- GRP1 co-localizes with ARF6 and regulates GTP/GDP exchange.
- It interacts with PtdIns(3,4,5)P3 at the plasma membrane and may act as its receptor.
- GRP1 may also regulate protein sorting, membrane trafficking, and cell adhesion through integrin interaction.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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