Thermo Fisher Scientific GNAI3 Polyclonal Antibody
GNAI3 단백질을 특이적으로 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC/IF에 적합하며, 인간, 마우스, 랫트 시료에 반응. 고순도 친화 크로마토그래피 정제, PBS/glycerol buffer로 안정 저장 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GNAI3 (Accession P08754), corresponding to amino acid residues L39–G89 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2851058 |
Product Specific Information
This antibody detects endogenous levels of total GNAI3.
Target Information
Heterotrimeric G proteins relay information from cell surface receptors to intracellular effectors. Each receptor detects specific extracellular stimuli such as photons, pheromones, odorants, hormones, or neurotransmitters, while effectors like adenyl cyclase generate intracellular messengers.
In mammals, G protein alpha, beta, and gamma subunits are encoded by at least 16, 4, and 7 genes, respectively. The alpha subunits bind and hydrolyze GTP and regulate effector activity. Four main classes of Galpha subunits exist: Gs, Gi, Gq, and Galpha12/13.
The Gi class includes all alpha subunits susceptible to pertussis toxin modification (Galpha i-1, i-2, i-3, o, t1, t2, z, gust). Among these, the three Galpha i subtypes function to open atrial potassium channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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