
Thermo Fisher Scientific Lambda light chain Humanized Recombinant Human Monoclonal Antibody (SAA0488)
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Applications
Tested Dilution
Publications
Western Blot (WB)
Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
Assay-dependent
Immunocytochemistry (ICC/IF)
Assay-dependent
ELISA (ELISA)
Assay-dependent
Immunoprecipitation (IP)
Assay-dependent
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Human / VHH-hFc
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
SAA0488
Immunogen
Recombinant Mouse Lambda Chain.
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Specific Information
Compatible with Direct ELISA
Target Information
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin`s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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