Thermo Fisher Scientific Lambda light chain Humanized Recombinant Human Monoclonal Antibody (SAA0488)
Thermo Fisher의 인간화 재조합 단일클론 항체로, Mouse Lambda light chain을 인식합니다. Western blot, IHC, ICC, ELISA, IP 등 다양한 면역분석에 사용 가능합니다. CHO 세포 발현, Protein A/G 정제, PBS 버퍼에 보존된 액상 형태입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Human / VHH-hFc |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA0488 |
| Immunogen | Recombinant Mouse Lambda Chain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa).
Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region.
The ratio of kappa to lambda is 70:30.
Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas.
Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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