Thermo Fisher Scientific MMP19 Polyclonal Antibody
MMP19 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. IHC(P) 등 다양한 응용에 적합하며, 인간·마우스·랫트 반응성을 보입니다. 고순도 항원 친화 크로마토그래피로 정제되어 안정적인 신뢰성을 제공합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide, corresponding to amino acids 12–60 of Human MMP-19 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2802976 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
MMP-19 (RASI-1, MMP-18) is a 508 amino acid peptide, originally isolated as an autoantigen from the synovium of a patient suffering from rheumatoid arthritis (RA). Its presence on activated PBMCs, TH1 lymphocytes, and Jurkat T lymphoma cells suggests a role in RA-associated joint tissue destruction.
MMP-19 is expressed in smooth muscle cells of the tunica media of large blood vessels in RA patients but not in endothelial layers. Acutely inflamed synovial capillaries strongly express MMP-19, indicating involvement in angiogenesis.
MMP-19 is a single 2.7 kb transcript found in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis, colon, and heart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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