Thermo Fisher Scientific TIMP2 Monoclonal Antibody (OTI3G7), TrueMAB
TIMP2 단백질을 인식하는 Mouse Monoclonal Antibody로 Western Blot에 적합. Human 시료 반응성. Lyophilized 형태로 제공되며, PBS buffer와 trehalose 포함. 재구성 및 conjugation 실험에 용이. 연구용 전용 제품.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G7 |
| Immunogen | Full length human recombinant protein of human TIMP2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, an additional desalting step is recommended (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
TIMP-1 and TIMP-2 are inhibitory enzymes of the matrix metalloproteinase family, crucial for maintaining connective tissue integrity.
TIMP-2 binds to both latent (pro) and active forms of 72 kDa Type IV collagenase (MMP-2 or gelatinase A) and the active form of 92 kDa Type IV collagenase (MMP-9 or gelatinase B).
It inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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