Thermo Fisher Scientific Phospho-CD171 (Ser1181) Polyclonal Antibody
Phospho-CD171 (Ser1181) 폴리클로날 항체로, 인간 CD171/N-CAML1의 인산화 부위(Ser1181)를 인식합니다. Western blot에 적합하며, Rabbit IgG 기반의 비결합형 액상 항체입니다. 신경계 발달 연구 및 L1CAM 관련 단백질 분석에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human CD171/N-CAML1 around the phosphorylation site of Ser1181 (L-E-SP-D-N) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555043 |
Target Information
L1CAM/CD171 is an axonal glycoprotein belonging to the immunoglobulin supergene family.
The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like type III repeats, is linked via a single transmembrane sequence to a conserved cytoplasmic domain.
This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation.
Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia, and hydrocephalus).
Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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