Thermo Fisher Scientific TAX1BP1 Polyclonal Antibody
TAX1BP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에서 2 µg/mL로 검증됨. 인간 시료 반응성, Protein G 정제, PBS/BSA buffer에 보관. TNF 유도 세포사멸 억제 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Amino acids 718–735 (CSEQFPPDYDQQVFERHV) of human TRAF6BP (TAX1BP) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2198927 |
Product Specific Information
- Suggested positive control: Raji whole cell lysate.
Target Information
This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3 and inhibits TNF-induced apoptosis by mediating TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with TNF-induced apoptosis. It may also play a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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