Thermo Fisher Scientific RAD23B Monoclonal Antibody (OTI7G10), TrueMAB
RAD23B 단백질을 인식하는 Mouse monoclonal antibody로, Western blot 및 IHC(P) 검증 완료. 인간 단백질 반응성. 1 mg/mL 농도의 액상 형태로 제공되며, PBS 기반 버퍼에 50% glycerol 포함. -20°C 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7G10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1-253 of human RAD23B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). It is a component of the protein complex that complements the NER defect of xeroderma pigmentosum group C (XP-C) cell extracts in vitro.
This protein interacts with and enhances the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), suggesting a role in DNA damage recognition in base excision repair.
It contains an N-terminal ubiquitin-like domain that interacts with the 26S proteasome, indicating involvement in the ubiquitin-mediated proteolytic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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