Thermo Fisher Scientific RAD23B Monoclonal Antibody (OTI12C10), TrueMAB
RAD23B 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합. 인간 시료에 반응하며, 고순도 친화 크로마토그래피 정제. 액상 형태로 안정한 PBS/BSA/glycerol 버퍼에 보관. DNA 손상 복구 연구용으로 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI12C10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–253 of human RAD23B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The RAD23B gene encodes a human homolog of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). RAD23B participates in protein complexes that complement the NER defect of xeroderma pigmentosum group C (XP-C) cells and interacts with 3-methyladenine-DNA glycosylase (MPG), suggesting a role in DNA damage recognition during base excision repair. The protein’s N-terminal ubiquitin-like domain interacts with the 26S proteasome, indicating involvement in the ubiquitin-mediated proteolytic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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