Thermo Fisher Scientific PPAR Delta Polyclonal Antibody
PPAR delta 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, ELISA, IP 등 다양한 응용에 사용 가능. 마우스 및 랫트 반응성. 친화 크로마토그래피로 정제된 액상 형태이며, -20°C에서 보관. 연구용으로만 사용.
- 카탈로그번호
- 600-401-420
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PPAR Delta Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:500 |
| ELISA | 1:30,000–1:70,000 |
| Immunoprecipitation (IP) | 1:500–1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Anti-PPAR delta antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the amino terminus of mouse PPAR delta. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
Directed against mouse PPAR delta protein. A BLAST analysis suggests reactivity with this protein from mouse and rat sources based on 100% homology for the immunogen sequence.
Cross-reactivity with PPAR delta protein from human, chimpanzee, and rabbit may occur (85% homology). No reactivity is expected against other subtypes of PPAR.
Target Information
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells.
PPARs mediate a variety of biological processes and may be involved in the development of chronic diseases such as diabetes, obesity, atherosclerosis, and cancer.
This protein acts as an inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma, functioning as an integrator of transcription repression and nuclear receptor signaling.
Expression is elevated in colorectal cancer cells and can be repressed by adenomatosis polyposis coli (APC). Knockout studies in mice indicate roles in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.