Thermo Fisher Scientific CEACAM1 (CEA Cell Adhesion Molecule 1) Monoclonal Antibody (CEACAM1/4843)
인체 CEACAM1 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, IHC(P) 및 Peptide Array에 사용 가능. 세포막 및 분비 위치 검출에 적합하며, Protein A/G 정제 및 200 µg/mL 농도로 제공. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CEACAM1/4843 |
| Immunogen | Recombinant fragment (around aa 50–250) of human CEACAM1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Endometrium, human colon, liver, or hepatic carcinoma tissues
- Cellular Location: Secreted; Cell membrane; Localizes to sites of cell-cell contact
Target Information
CEACAM1 is a member of the carcinoembryonic antigen (CEA) gene family, belonging to the immunoglobulin superfamily. The CEA cell adhesion molecules and pregnancy-specific glycoproteins are located within a 1.2 Mb cluster on chromosome 19. CEACAM1 was initially described in liver bile ducts as biliary glycoprotein and later found on leukocytes, epithelia, and endothelia. It mediates cell adhesion through homophilic and heterophilic interactions, contributing to tissue differentiation, angiogenesis, apoptosis, tumor suppression, metastasis, and immune modulation. Multiple transcript variants exist, with two full-length forms characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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