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Thermo Fisher Scientific CEACAM1 (CEA Cell Adhesion Molecule 1) Monoclonal Antibody (CEACAM1/4837)
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Thermo Fisher Scientific CEACAM1 (CEA Cell Adhesion Molecule 1) Monoclonal Antibody (CEACAM1/4837)

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Human CEACAM1 단백질을 인식하는 Mouse 단일클론 항체로, IHC(P)에서 1–2 µg/mL로 사용 가능. 단백질 A/G로 정제된 액상형 항체이며, PBS + 0.05% BSA 버퍼에 보관. 세포막 및 세포 간 접촉 부위에 위치하는 CEACAM1 검출에 적합.

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pk
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Thermo Fisher Scientific 634-MSM7-P0 CEACAM1 (CEA Cell Adhesion Molecule 1) Monoclonal Antibody (CEACAM1/4837) 20 ug pk판매 단위 pk
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411,600원VAT 포함 452,760원

Thermo Fisher Scientific · Thermo Fisher Scientific CEACAM1 (CEA Cell Adhesion Molecule 1) Monoclonal Antibody (CEACAM1/4837)

Applications

Immunohistochemistry (Paraffin) (IHC (P))

  • Tested Dilution: 1–2 µg/mL

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG2, kappa
Class Monoclonal
Type Antibody
Clone CEACAM1/4837
Immunogen Recombinant fragment (around aa 50–250) of human CEACAM1 protein (CD66a, UniProt ID: P13688-1)
Conjugate Unconjugated
Form Liquid
Concentration 200 µg/mL
Purification Protein A/G
Storage Buffer PBS with 0.05% BSA
Contains 0.05% sodium azide
Storage Conditions 4°C
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • Positive Control: Endometrium; Human colon, liver, or hepatic carcinoma tissues
  • Cellular Location: Secreted; Cell membrane; Localizes to sites of cell–cell contact

Target Information

CEACAM1 (CEA Cell Adhesion Molecule 1) is a member of the carcinoembryonic antigen (CEA) gene family within the immunoglobulin superfamily.
It is located on chromosome 19 within a 1.2 Mb cluster containing CEA cell adhesion molecules and pregnancy-specific glycoproteins.
Originally identified as biliary glycoprotein in liver bile ducts, CEACAM1 functions as a cell–cell adhesion molecule found on leukocytes, epithelial, and endothelial cells.
It mediates homophilic and heterophilic interactions and plays roles in:

  • Tissue differentiation and structural organization
  • Angiogenesis and apoptosis
  • Tumor suppression and metastasis
  • Modulation of innate and adaptive immune responses

Multiple transcript variants exist, with two full-length isoforms characterized.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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