Thermo Fisher Scientific TFF2 Monoclonal Antibody (4G7C3)
TFF2 단백질을 인식하는 Mouse monoclonal antibody (clone 4G7C3). Western blot, Flow cytometry, ELISA 등에 적합. 인간 시료 반응성. Protein G 정제, PBS buffer에 0.05% sodium azide 포함. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4G7C3 |
| Immunogen | Purified recombinant fragment of human TFF2 (AA: 20–125) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787553 |
Product Specific Information
MA5-31930 has been tested in indirect ELISA.
Target Information
Trefoil peptides are protease-resistant molecules secreted throughout the gut that play a role in mucosal healing and protection of the gastrointestinal epithelia. These peptides contain three intrachain disulfide bonds forming the trefoil motif (P-domain).
SP (spasmolytic polypeptide), also known as Trefoil factor 2 (TFF2) precursor, is a trefoil protein that inhibits gastrointestinal motility and gastric acid secretion. SP may act as a structural component of gastric mucus by stabilizing glycoproteins through interactions with carbohydrate side chains.
Downregulation of SP expression is associated with primary gastric cancer, and progressive loss of this protein is likely involved in early stages of gastric carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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