Thermo Fisher Scientific CPB2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 115-365 of human CPB2 (NP_001863.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Carboxypeptidase B2,uniProtId:Q96IY4-1,ncbiNodeId:9606,antigenRange:115-365,antigenLength:423,antigenImageFileName:PA5-109580_Carboxypeptidase_B2_Q96IY4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-109580_Carboxypeptidase_B2_Q96IY4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.15 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2854991

Product Specific Information

Immunogen sequence: ASASYYEQYH SLNEIYSWIE FITERHPDML TKIHIGSSFE KYPLYVLKVS GKEQAAKNAI WIDCGIHARE WISPAFCLWF IGHITQFYGI IGQYTNLLRL VDFYVMPVVN VDGYDYSWKK NRMWRKNRSF YANNHCIGTD LNRNFASKHW CEEGASSSSC SETYCGLYPE SEPEVKAVAS FLRRNINQIK AYISMHSYSQ HIVFPYSYTR SKSKDHEELS LVASEAVRAI EKTSKNTRYT HGHGSETLYL A

Target Information

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.