Thermo Fisher Scientific PTPN11/Shp2 Polyclonal Antibody
PTPN11/Shp2 단백질을 인식하는 Rabbit Polyclonal Antibody로서 WB 및 IP에 적합. 인간 단백질 543-593 영역을 면역원으로 제작. 1 mg/mL 농도의 액상 형태이며 4°C 보관. 세포 신호 조절 및 암 연구 등 다양한 생물학적 연구용으로 사용 가능.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 543 and 593 of Human tyrosine-protein phosphatase non-receptor type 11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Chicken
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP contains two tandem Src homology-2 domains that mediate phospho-tyrosine binding and substrate interaction.
It is widely expressed in most tissues and plays a regulatory role in cell signaling events important for mitogenic activation, metabolic control, transcription regulation, and cell migration.
Mutations in this gene are associated with Noonan syndrome and acute myeloid leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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