Thermo Fisher Scientific HNF6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:100

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 167-292 of human ONECUT1 (NP_0044891) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HNF6,uniProtId:Q9UBC0-1,ncbiNodeId:9606,antigenRange:167-292,antigenLength:465,antigenImageFileName:PA5-88749_HNF6_Q9UBC0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88749_HNF6_Q9UBC0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.6 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805102

Product Specific Information

Immunogen sequence: PYHKDVAGMG QSLSPLSSSG LGSIHNSQQG LPHYAHPGAA MPTDKMLTPN GFEAHHPAML GRHGEQHLTP TSAGMVPING LPPHHPHAHL NAQGHGQLLG TAREPNPSVT GAQVSNGSNS GQMEEI; Positive Samples: Jurkat, Mouse brain, Mouse spleen, Mouse testis, Rat brain; Cellular Location: Nucleus

Target Information

Hepatocyte nuclear factor 6 is a CUT homeobox family protein which is a transcription factor and contains a CUT DNA-binding domain and a homeobox DNA-binding domain. It is an upstream regulator of several genes involved in the pathogenesis of maturity-onset diabetes of the young. HNF6 is a ligand of the FOXM1 transcription factor network. HNF6, along with HNF4, controls gene expression in the liver. The expression levels of HNF6 and HNF4 rise steadily during development and that up- or down regulation of HNF6 and HNF4 expression generate premature or delayed expression of the g6pc gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.