Thermo Fisher Scientific HNF6 Polyclonal Antibody
HNF6 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에 반응합니다. Western blot, ICC/IF, ELISA에 적합하며, 고순도 Affinity Chromatography로 정제되었습니다. 핵 내 HNF6 단백질 검출 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 167–292 of human ONECUT1 (NP_0044891) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.6 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805102 |
Product Specific Information
Immunogen sequence:
PYHKDVAGMG QSLSPLSSSG LGSIHNSQQG LPHYAHPGAA MPTDKMLTPN GFEAHHPAML GRHGEQHLTP TSAGMVPING LPPHHPHAHL NAQGHGQLLG TAREPNPSVT GAQVSNGSNS GQMEEI
Positive Samples: Jurkat, Mouse brain, Mouse spleen, Mouse testis, Rat brain
Cellular Location: Nucleus
Target Information
Hepatocyte nuclear factor 6 (HNF6) is a CUT homeobox family transcription factor containing both CUT and homeobox DNA-binding domains. It regulates genes involved in maturity-onset diabetes of the young and interacts with the FOXM1 transcription factor network. HNF6, together with HNF4, controls gene expression in the liver, with expression levels increasing during development. Dysregulation of HNF6 and HNF4 expression can lead to premature or delayed expression of the g6pc gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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