Thermo Fisher Scientific PFKFB2 Polyclonal Antibody
Human PFKFB2 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS 기반 완충액에 보존. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- PA583985
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PFKFB2. Recombinant protein control fragment (Product #RP-101243) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791137 |
Product Specific Information
Immunogen sequence:
RDKPTNNFPK NQTPVRMRRN SFTPLSSSNT IRRPRNYSVG SRPLKPLSPL RAQDMQEG
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the γ phosphate of ATP, onto an acceptor amino acid in a substrate protein. Through this mechanism, protein kinases mediate most signal transduction in eukaryotic cells, regulating metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.
The protein kinase family, with more than 500 gene products, is one of the largest in eukaryotes. It is classified into 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
The AGC kinase group includes 63 kinases such as:
- Cyclic nucleotide-regulated protein kinases (PKA & PKG)
- Diacylglycerol-activated/phospholipid-dependent protein kinases (PKC)
- RAC/Akt protein kinase family
- ARK family (phosphorylates G protein-coupled receptors)
- RSK family (phosphorylates ribosomal protein S6)
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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