Thermo Fisher Scientific RAB6A/RAB6C Polyclonal Antibody
RAB6A/RAB6C 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB 및 IHC(P) 적용 가능. 인간, 마우스, 랫트 반응성. 동결건조 형태로 보관 안정성 우수. 연구용 전용 시약.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 | - |
| Miscellaneous PubMed (Misc) | - | View 3 publications |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the C-terminal region of human Ras-related protein Rab-6A (RAB6A) conjugated to an immunogenic carrier protein. The antigen shares 85% identity with RAB6C. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: RAB6A and RAB6C.
Target Information
GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments.
This protein is located at the Golgi apparatus and regulates trafficking in both retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and anterograde (from the Golgi to the plasma membrane) directions.
Myosin II acts as an effector in these processes.
It is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein pp150.
Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
[provided by RefSeq, Aug 2011]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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