
Thermo Fisher Scientific ZBED3 Polyclonal Antibody
인간 ZBED3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. IHC(P) 및 ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS, 40% 글리세롤, 0.02% 아지드 함유. Wnt/β-catenin 경로 연구용으로 권장됩니다.
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- PA563231
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
- Publications: References
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZBED3. Recombinant protein control fragment (Product #RP-95509) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649749 |
Product Specific Information
Immunogen sequence:
RELQAEREAL QARLRDVSRR EGALGWAPAA PPPLKDDPEG DRDGCVITKV LL
Highest antigen sequence identity to the following orthologs:
- Mouse: 31%
- Rat: 40%
Target Information
Axin is a key modulator of the Wnt/β-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic β-catenin.
ZBED3, a member of the Zinc finger BED-type domain-containing superfamily, has been identified as an Axin-interacting protein and is suggested to modulate the Wnt/β-catenin signaling pathway.
RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced β-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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