Thermo Fisher Scientific CASKIN1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

-

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Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunohistochemistry (Frozen) (IHC (F))

-

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Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

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Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CASKIN1. Recombinant protein control fragment (Product #RP-101673). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CASKIN1,uniProtId:Q8WXD9-1,ncbiNodeId:9606,antigenRange:2-52,antigenLength:1431,antigenImageFileName:PA5-63228_CASKIN1_Q8WXD9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63228_CASKIN1_Q8WXD9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639307

Product Specific Information

Immunogen sequence: GKEQELVQAV KAEDVGTAQR LLQRPRPGKA KLLGSTKKIN VNFQDPDGFS A

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Target Information

Calcium/calmodulin-dependent serine protein kinase (CASK) is a conserved multi-domain scaffolding protein involved in brain development, synapse formation, and establishment of cell polarity. CASKINs (CASK interacting proteins) interact with CASK and is thought to play a role in CASK function, specifically by coupling CASK to distinct downstream effectors. CASKIN1 is a multidomain protein containing six N-terminal ankyrin repeats, one SH3 domain, and two sterile alpha motif domains followed by a long proline-rich sequence and a short conserved C-terminal domain. CASKIN1 coassembles with CASK on the cytoplasmic tail of neurexin 1, suggesting that CASKIN and CASK coat the cytoplasmic tails of neurexins and other cell-surface proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.