Thermo Fisher Scientific TLK1 Polyclonal Antibody
TLK1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 사용 가능. Human에 반응하며 Monkey, Rabbit, Rat에서도 예측 반응. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 2 publications |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | — |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptides corresponding to human TLK1 (aa348–aa367 and aa107–aa122) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 30% glycerol, 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725528 |
Product Specific Information
This antibody is predicted to react with Monkey, Rabbit, and Rat.
Target Information
TLK1 (Tousled-like kinase 1) is a nuclear serine/threonine kinase involved in the regulation of chromatin assembly. It was first described in Arabidopsis. TLK1 is a target of the DNA damage checkpoint and is rapidly inactivated upon exposure to ionizing radiation (IR). This inactivation is mediated by the S-phase DNA damage checkpoint. TLK1 activity suppression after DNA double-strand breaks, replication blockade, or UV irradiation requires ATM, NBS, and CHK1. Tousled-like kinases are nuclear kinases potentially involved in chromatin assembly regulation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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