Thermo Fisher Scientific SULT1A1 Monoclonal Antibody (OTI5F1)
인간 SULT1A1 단백질을 인식하는 Mouse IgG1 단클론 항체로 다양한 응용(WB, IHC, ICC/IF, Flow)에 사용 가능. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F1 |
| Immunogen | Full length human recombinant protein of SULT1A1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725445 |
Target Information
The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens, and the regulation of hormones by catalyzing the sulfate conjugation of these substances. Members of the three groups comprising this superfamily (SULT1, SULT2, and SULT3) show selectivity to certain substrate compounds.
SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), also known as STP or STP1, is a 295 amino acid protein localized in the cytoplasm and belongs to the sulfotransferase family. It functions as a homodimer expressed in brain, liver, skin, and lung tissue. SULT1A1 catalyzes the sulfate conjugation of catecholamines, phenolic drugs, and neurotransmitters, playing a role in the elimination of various compounds from the body. Additionally, it may be involved in the activation of carcinogenic N-hydroxyarylamines, suggesting a possible role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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