Thermo Fisher Scientific RAD1 Monoclonal Antibody (1G2)
RAD1 단백질을 표적으로 하는 Thermo Fisher Scientific의 1G2 클론 단일클론 항체입니다. Western blot, IHC, ELISA에 최적화되어 있으며 인간 시료에 반응합니다. 액상 형태로 제공되며 방부제 무첨가, -20°C 보관 조건을 권장합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G2 |
| Immunogen | RAD1 (AAH06837, 1–90 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MPLLTQQIQD EDDQYSLVAS LDNVRNLSTI LKAIHFREHA TCFATKNGIK VTVENAKCVQ ANAFIQAGIF QEFKVQEESV TFRINLTVLL
Target Information
Rad1 is a component of a heterotrimeric PCNA-like complex that contains Rad9 and Hus1 proteins. This complex is involved in the 9-1-1 cell cycle checkpoint response, playing a major role in DNA repair by associating with Rad17 and several components of the PCNA-loading heteropentamer replication factor C. Mutants have been shown to partially restore radiation resistance and G2-checkpoint activity. It has also been shown to possess exonuclease activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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